Hypopituitarism and panhypopituitarism can be congenital or acquired. Congenital hypopituitarism is usually present in children, hence will not be discussed in detail. However, some patient, when grown in adulthood, may come under care of physician.
Adult-onset Panhypopituitarism in Animals. By. Deborah S. Greco, DVM, PhD, DACVIM-SAIM, Nestle Purina PetCare. Nonfunctional tumors of the pituitary gland may lead to panhypopituitarism as the growth of a neoplastic, but nonsecretory, cell type displaces other pituitary cells. Signs related to the loss of gonadal, thyroid, and adrenocortical.
Panhypopituitarism that results from genetic mutation can have normal neuroimaging results, but the defects appear early in the life and not in the adulthood . Of all the different causative conditions for adult hypopituitarism, pituitary adenoma and its treatment either by surgery or radiation therapy is found to be most frequently seen.